Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Due to the high reactivity of the TDI substances with water, bioaccumulation tests can in principle not be performed with these substances. However, one bioaccumulation test (OECD 305E) with 2,4-TDI and a mesocosm study with PMDI with no indication of bioaccumulation potential have been performed.

No data are available on terrestrial bioaccumulation on TDI. The reactivity of TDI with water, the low measured BCF in fish and the evidence of the mesocosm study, suggest that TDI has a low potential to bioaccumulate in terrestrial food-chains.