Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 218-216-0 | CAS number: 2082-79-3
Ecotoxicological information
Toxicity to terrestrial plants
Currently viewing:
Administrative data
- Endpoint:
- toxicity to terrestrial plants: short-term
- Type of information:
- experimental study
- Adequacy of study:
- disregarded due to major methodological deficiencies
- Study period:
- 1991-09-05 to 1991-09-23 (test period)
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: GLP-guideline study. Some experimental details are missing in the report (e.g. number of seeds per pot is not mentioned, number of replicates etc). The calculations of EC50 concentrations is not assignable for the reviewer.
Data source
Referenceopen allclose all
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 991
- Report date:
- 1991
- Reference Type:
- secondary source
- Title:
- SIDS Initial Assessment Report For SIAM 22, Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate, CAS: 2082-79-3
- Author:
- OECD
- Year:
- 2 006
- Bibliographic source:
- UNEP Publications
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 208 (Terrestrial Plants Test: Seedling Emergence and Seedling Growth Test)
- Deviations:
- yes
- Remarks:
- percent particles <= 20 µm not determined; organic matter content > 3% of dry weight
- GLP compliance:
- yes
Test material
- Reference substance name:
- Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
- EC Number:
- 218-216-0
- EC Name:
- Octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
- Cas Number:
- 2082-79-3
- Molecular formula:
- C35H62O3
- IUPAC Name:
- octadecyl 3-(3,5-di-tert-butyl-4-hydroxyphenyl)propionate
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test substrate
- Vehicle:
- no
- Details on preparation and application of test substrate:
- - Method of mixing into soil (if used): 637.5 mg test substance were mixed with 6503 g of oven dried test soil in a HOBART blender. The stock mixture was directly used for the highest test concentration (100 mg/kg). In order to achieve the test concentrations of 1 mg/kg, 650 g of the stock mixture were mixed with the 5852 g of oven dried test soil (dilution 1:10). Then 650 g of the dilution 1:10 were mixed with 5852 g of oven dried test soil to obtain the lowest test concentration of 1 mg/kg. After dispensing the blends into the test containers the seeds were planted and covered with a thin layer of test soil. The water was added subsequently.
- Controls: Blank
Test organisms
open allclose all
- Species:
- Brassica rapa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: turnip
- Plant family: Brassicaceae
- Source of seed: Eric Schweizer AG, CH-3602 Thun
- Species:
- Lolium perenne
- Plant group:
- Monocotyledonae (monocots)
- Details on test organisms:
- - Common name: ryegrass
- Plant family: Poaceae
- Source of seed: Eric Schweizer AG, CH-3602 Thun
- Species:
- Vicia sativa
- Plant group:
- Dicotyledonae (dicots)
- Details on test organisms:
- - Common name: vetch
- nitrogen-fixing plant
- Plant family: Fabaceae
- Source of seed: Eric Schweizer AG, CH-3602 Thun
Study design
- Test type:
- seedling emergence toxicity test
- Study type:
- laboratory study
- Substrate type:
- natural soil
- Limit test:
- no
- Total exposure duration:
- 19 d
Test conditions
- Moisture:
- 65% water retention capacity
- Details on test conditions:
- TEST SYSTEM
- Test container: non-porous plant pots with an upper internal diameter of 90 mm
- Amount of soil: Approx. 450 g dry soil
- No. of seeds per container: not stated, total number 20
- No. of replicates per treatment group: not stated
- No. of replicates per control: not stated
SOURCE AND PROPERTIES OF SUBSTRATE
80 % "Loess" and 20 % fine quartz sand, not sterilised soil with the following characteristics :
- pH : 6.9
- organic matter content : 4 %
GROWTH CONDITIONS
Air humidity: 42-88 %
Duration : 19 days
Type of testing facility: growth chamber
Watering : Humidity of soil was maintained during exposure at 65 % water retention capacity (corresponding to 7.3-20.4 % humidity in soil during the test, all species together) with daily control of
weight (pot including soil, water, plant) from Monday to Friday.
EFFECT PARAMETERS MEASURED :
Observations:
- Number of seedlings and any observable effects on appearance and growth.
Measurements:
- Dry weight of plant: Determination by drying for 24 hours at a temperature of 70°C to a constant
weight and reweighing.
- Soil Moisture: Determination by drying a small sample at a temperature of approx. 120°C to a
constant weight at the start and the end of exposure. Moisture is expressed as % of dry weight of soil,
- Air temperature and moisture: continuous Soil pH: pH-electrode / at the start and the end of exposure
- Organic matter content: determined with a soil sample (about 20 g) by weight difference between 120°C and 550°C. - Nominal and measured concentrations:
- 1, 10, 100 mg test substance/kg d.w.
- Reference substance (positive control):
- no
Results and discussion
Effect concentrationsopen allclose all
- Species:
- Brassica rapa
- Duration:
- 19 d
- Dose descriptor:
- EC50
- Effect conc.:
- 24 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Species:
- Brassica rapa
- Duration:
- 19 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Lolium perenne
- Duration:
- 19 d
- Dose descriptor:
- EC50
- Effect conc.:
- 50 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth
- Species:
- Lolium perenne
- Duration:
- 19 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- seedling emergence
- Species:
- Vicia sativa
- Duration:
- 19 d
- Dose descriptor:
- EC50
- Effect conc.:
- > 100 mg/kg soil dw
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- other: growth and seedling emergence
Any other information on results incl. tables
Some visible effects were observed on turnip at 100 mg/kg (dried leeves).
Applicant's summary and conclusion
- Validity criteria fulfilled:
- no
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
