Registration Dossier
Registration Dossier
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EC number: 423-270-5 | CAS number: 164462-16-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
With high probability the test substance is acutely not harmful to aquatic algae.
Key value for chemical safety assessment
Additional information
The toxicity of the test substance on the green algae Scenedesmus subspicatus was measured in 4 GLP guideline studies [BASF AG, 1995 and 1998]. The test substance is a complexing agent which can dispose micronutrients from the culture medium. Therefore algae growth can be significantly reduced under standardized guideline conditions and may yield apparent results that are more or less severe than the true toxicity (see Guidance on Hazard to the Aquatic Environment Globally Harmonized System GHS Annex 9 A9.3.3.4, 2007). To compensate this effect, the algae studies with Scenedesmus subspicatus were performed in nutrient- enriched media with CaCl2 and CaCO3 or FeCl3. As the EC10 and EC50 values for the growth rate with nutrient- enriched media determined to be > 100 mg/L, the measured algae toxicity under standardized guideline conditions was caused by nutrient limitation and can be assessed as a secondary effect.
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