Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
No effects were observed and thus the 96h-LC50 was considered to exceed the maximum solubility of the test substance in medium.
Key value for chemical safety assessment
Additional information
The acute toxicity to Medaka was examined under static conditions in a test that was carried out according to OECD 203 and GLP.
The test was carried out at a limit test with a nominal concentration of 100 mg/L. The test substance and dilution water were mixed and they were stirred by magnetic stirrer for about 48h at 20°C. At the start and the end of the test, samples were taken from the middle of the vessel and analysed by HPLC-UV.
At the start of the exposure, the test medium was yellow and suspended and floating substance were observed. The appearance of the test solution remained unchanged until the end of the exposure.
The measured concentration was 0.032 mg/L at the start and 0.018 mg/L at the end of the test. The geometric mean measured concentration was 0.024 mg/L.
No effects were observed and thus the 96h-LC50 was considered to exceed the maximum solubility of the test substance in medium.
The validity criteria were fulfilled.
The study is considered reliable without restriction
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