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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Remarks:
Test procedure according to method of Analytical Expert Group ETAD (Ecological and Toxicological Association of Dyes and Organic Pigment Manufacturer)
Cross-reference
Reason / purpose for cross-reference:
reference to same study
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
comparable to guideline study with acceptable restrictions
Remarks:
test procedure similar to OECD 105
Reason / purpose for cross-reference:
reference to same study
Qualifier:
equivalent or similar to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
yes
Remarks:
modified taking into account the very low water solubility of the test substance
Principles of method if other than guideline:
Determination of water solubility by UV-vis spectrometry
Type of method:
flask method
Water solubility:
3.5 µg/L
Temp.:
24 °C
pH:
ca. 7
Details on results:
The value given refers to room temperature (24-25 °C, see above) and represents the mean from 3 determinations (sigma = 0.6). Individual values were: 3.2, 3.1 and 4.1 µg/L.
Conclusions:
The test substance is practically insoluble in water (< 0.1 mg/L)
Executive summary:

The water solubility of the test substance was determined using UV-vis spectrometry. The water solubility at 24 -25 °C was 3.5 µg/L.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: ETAD Analytical Expert Group
Version / remarks:
method for substances with very low solubility in both water and n-octanol
Principles of method if other than guideline:
Determination of solubility in octanol and calculation of log Pow with water solubility
Type of method:
estimation method (solubility ratio)
Partition coefficient type:
octanol-water

Test material

Constituent 1
Chemical structure
Reference substance name:
Reaction mass of 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)-3-oxobutyramide] and 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide] and 2-[[3,3'-dichloro-4'-[[1-[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-3-oxo-N-(o-tolyl)butyramide (EC 911-715-0)
EC Number:
911-715-0
Molecular formula:
C34H30Cl2N6O4 // C35H32Cl2N6O4 // C36H34Cl2N6O4
IUPAC Name:
Reaction mass of 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2,4-dimethylphenyl)-3-oxobutyramide] and 2,2'-[(3,3'-dichloro[1,1'-biphenyl]-4,4'-diyl)bis(azo)]bis[N-(2-methylphenyl)-3-oxobutyramide] and 2-[[3,3'-dichloro-4'-[[1-[[(2,4-dimethylphenyl)amino]carbonyl]-2-oxopropyl]azo][1,1'-biphenyl]-4-yl]azo]-3-oxo-N-(o-tolyl)butyramide (EC 911-715-0)
Test material form:
solid: nanoform

Study design

Analytical method:
photometric method

Results and discussion

Partition coefficientopen allclose all
Type:
Pow
Partition coefficient:
5.43
Temp.:
24 °C
pH:
ca. 7
Type:
log Pow
Partition coefficient:
0.73
Temp.:
24 °C
pH:
ca. 7
Details on results:
Pow and log Pow were calculated from equilibrium concentrations in n-octanol (see below) and in water (see section 4.8)

Any other information on results incl. tables

The solubility in n-octanol was determined to be 19 µg/L at ambient temperature (24 -25°C). This figure represents the mean of 3 determinations (range: 19 -21 µg/L, sigma = 2). The solubility in water was determined to be 3.5 µg/L (section 4.8).These solubilities (equilibrium concentrations considering the tests performed) are used to calculate Pow with the following equation:

Pow = equilibrium concentration in octanol / equilibrium concentration in water

Pow = 19 µg/L / 3.5 µg/L

Pow = 5.43

log Pow = 0.73

Applicant's summary and conclusion

Conclusions:
The test item has a log Pow of 0.73.
Executive summary:

The log Pow of the test substance was calculated from the equilibrium concentrations in water and in n-octanol. The log Pow at 24 -25 °C was 0.73.