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EC number: 261-385-0 | CAS number: 58670-89-6
Experimental studies of 5 representatives of the category of Guerbet alcohols show a very low acute oral toxicity. Mortalities were only observed after application of the shortest chain Guerbet alcohol 2 -Butyl-octan-1-ol (C12) but only at doses of about 15,000 mg/kg bw and above. No clinical symptoma were observed for Alcohols C16 -20, branched and longer chain guerbet alcohols after application of very high doses. No pathological findings were observed at dissection of the animals.
Acute dermal toxicity studies of C16 and C20 Guerbet alcohol also show a low dermal toxicity at doses of up to 2 ml/kg. The test substances were applied on intact as well as on scarificed skin with a damaged skin barrier. No deaths occurred at any of the doses applied. In case of the experiment with scarificed skin it should be considered that doses systemically available were actually much higher.
Based on the available data it can be concluded that all Guerbet alcohols of the category are of very low acute oral and dermal toxicity.
Available data are conclusive but not sufficient for classification of 2 -decyltetradecanol with regard to acute toxicity.
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