Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)
Additional information:

The comparison of the Stimulation Indexes between the treated groups and the control group revealed that the test substance Ashes (residues) – Biomass Combustion did not cause a significant increase in radioisotope incorporation into the DNA of proliferating lymphocytes.

In conclusion, at the given experimental conditions the result of LLNA study with test substance Ashes (residues) - Biomass Combustion was negative.

Based on the negative results of LLNA study of the test substance, it could be suggested, that the test substance does not have to be classified as the substance, which may cause sensitisation by skin contact.


Migrated from Short description of key information:
The test was performed according to the following method:
EU Method B.42, Skin sensitization: Local Lymph Node Assay, Council Regulation (EC) No. 440/2008, published in O.J. L142, 2008
GLP study

Justification for classification or non-classification