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Water solubility

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Endpoint:
water solubility
Type of information:
other: Handbook data
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
data from handbook or collection of data
Qualifier:
no guideline followed
Principles of method if other than guideline:
Handbook data - no method specified
GLP compliance:
no
Water solubility:
6.6 mg/L
Temp.:
20 °C
Water solubility:
11 mg/L
Temp.:
20 °C
Details on results:
The water solubilities of calcium carbonate are:

Aragonite and calcite: 6.6 mg/L at 20 °C
Vaterite: 11 mg/L at 20 °C
Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubilities of calcium carbonate are:

Aragonite and calcite: 6.6 mg/L at 20 °C
Vaterite: 11 mg/L at 20 °C
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
26 January 2010 to 04 March 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Deviations:
no
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Water solubility:
0.017 g/L
Temp.:
20 °C
pH:
9 - 9.4
Remarks on result:
other: Mean of 5 samples
Details on results:
The results for Samples 1 to 3 suggested that the water solubility was shaking time dependent; therefore, extra testing was carried out using longer shaking periods (Samples 4 and 5). However, the overall results for Samples 1 to 5 indicated that this was not the case.

Table 1: Concentration of test material in the sample solutions

Sample No.

Time shaken at ~30 °C (hours)

Time equilibrated at 20 °C (hours)

Concentration (g/L)

Solution pH

1

24

24

1.67 x 10-2

9.4

2

48

24

1.63 x 10-2

9.4

3

72

24

2.06 x 10-2

9.4

4

96

24

1.45 x 10-2

9.0

5

120

24

1.51 x 10-2

9.0

Conclusions:
Interpretation of results (migrated information): slightly soluble (0.1-100 mg/L)
The water solubility of calcium carbonate (conventional) has been determined to be 0.0166 g/L of solution at 20.0 ± 0.5 °C.

Description of key information

The water solubility of bulk calcium carbonate has been determined to be 0.0166 g/L of solution at 20.0 ± 0.5 °C.

Key value for chemical safety assessment

Water solubility:
16.6 mg/L
at the temperature of:
20 °C

Additional information

The water solubility of bulk calcium carbonate was determined to be 16.6 mg/L at 20 °C in a GLP study performed in accordance with OECD TG 105 (Walker & White, 2010). This result is supported by data from a peer reviewed handbook showing the solubility to be in the range of 6.6 -11 mg/L at 20 °C.