6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate

Guidance on Safe Use

First-aid measures

Eye Contact: Flush with water while holding eyelids open for at least 15 minutes. Seek medical attention if adverse symptoms appear.
Skin Contact: Remove contaminated clothing. Flush area with large amounts of water. Use soap. Seek medical attention if adverse symptoms appear.
Ingestion: Never give anything by mouth to an unconscious person. Wash out mouth with water. Do not induce vomiting unless directed by medical personnel. Seek medical attention.
Inhalation: Remove to fresh air and keep patient at rest. If breathing is difficult seek medical attention.

Fire-fighting measures

Extinguishing Media: Use carbon dioxide, foam, dry chemical, or water spray.
Hazardous Combustion Products: Formation of toxic gases is possible during heating or fire.
Fire Fighting Procedures: During all fire fighting activities, wear appropriate protective equipment, including selfcontained breathing apparatus.
Fire / Explosion Hazards: Fine particles (such as dust and mists) may fuel fires/explosions.

Accidental release measures

Health and Safety Precautions: Personnel involved in clean-up should wear appropriate personal protective equipment . Minimize exposure.
Measures for Cleaning / Collecting: Contain the source of spill if it is safe to do so. Collect spilled material by a method that controls dust generation.A damp cloth or a filtered vacuum should be used to clean spills of dry solids. Clean spill area thoroughly.
Measures for Environmental Protections: Place waste in an appropriately labeled, sealed container for disposal. Care should be taken to avoid environmental release.
Additional Consideration for Large Spills: Non-essential personnel should be evacuated from affected area. Report emergency situations immediately.Clean up operations should only be undertaken by trained personnel.

Handling and storage

General Handling: Restrict access to work area. Designate a change area to facilitate 'good manufacturing' decontamination practices. Ground and bond all bulk transfer equipment. No open handling permitted. All operations should be fully enclosed. Avoid inhalation and contact with skin, eye, and clothing. When handling, use appropriate personal protective equipment . Wash hands and any exposed skin after removal of PPE. Releases to the environment should be avoided.
Storage Conditions: Store at room temperature in properly labeled containers. Keep away from heat, sparks and flames.

Transport information

Shipping

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

Engineering Controls: Engineering controls should be used as the primary means to control exposures. Use process containment, local exhaust ventilation, or other engineering controls to maintain airborne levels below recommended exposure limits. All operations should be fully enclosed. No air recirculation permitted.
Personal Protective Equipment:
Hands: Wear impervious, disposable gloves as minimum protection (double recommended).
Eyes: Wear safety glasses as minimum protection.
Skin: Wear impervious disposable protective clothing when handling this compound.
Respiratory protection: wear an appropriate respirator with a protection factor sufficient to control the exposure .

Stability and reactivity

Stability: Stable at normal conditions
Conditions to Avoid: Fine particles (such as dust and mists) may fuel fires/explosions.
Incompatible Materials: Incompatible with acids and bases.
Polymerization: Will not occur

Disposal considerations

Dispose of waste in accordance with all applicable laws and regulations. Member State specific and Community specific provisions must be considered.