Registration Dossier

Toxicological information

Eye irritation

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Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
secondary literature

Data source

Reference
Reference Type:
review article or handbook
Title:
The Merck Index An Encyclopedia of Chemicals, Drugs, and Biologicals.
Author:
O'Neil, M.J. (ed.).
Year:
2001
Bibliographic source:
Edition, Whitehouse Station, NJ: Merck and Co., Inc., 2001., p. 536

Materials and methods

Principles of method if other than guideline:
No guideline specified
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Dichlone
EC Number:
204-210-5
EC Name:
Dichlone
Cas Number:
117-80-6
Molecular formula:
C10H4Cl2O2
IUPAC Name:
2,3-dichloro-1,4-dihydronaphthalene-1,4-dione

Test animals / tissue source

Species:
other: no data

Results and discussion

In vivo

Results
Irritation parameter:
other: not specified
Time point:
other: not specified
Score:
> 0

Any other information on results incl. tables

Irritating to skin, /and/ mucous membranes

Applicant's summary and conclusion