Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: dermal

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Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
no data
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Data derived from peer-reviewed handbook.

Data source

Reference
Reference Type:
review article or handbook
Title:
No information
Author:
Lewis, R (editor)
Year:
1996
Bibliographic source:
SAX's Dangerous Properties of Industrial Materials (Ninth edition)
Report date:
1996

Materials and methods

Principles of method if other than guideline:
No details are given on test protocol.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Pyridoxine hydrochloride
EC Number:
200-386-2
EC Name:
Pyridoxine hydrochloride
Cas Number:
58-56-0
Molecular formula:
C8H11NO3.ClH
IUPAC Name:
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol hydrochloride

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
3 000 mg/kg bw
Based on:
test mat.

Applicant's summary and conclusion