Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 204-129-5 | CAS number: 116-16-5
Partition coefficient
Administrative data
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: Guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2015
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
- Deviations:
- no
- GLP compliance:
- no
- Type of method:
- HPLC method
- Partition coefficient type:
- octanol-water
Test material
- Reference substance name:
- Hexachloroacetone
- EC Number:
- 204-129-5
- EC Name:
- Hexachloroacetone
- Cas Number:
- 116-16-5
- Molecular formula:
- C3Cl6O
- IUPAC Name:
- hexachloropropan-2-one
- Test material form:
- other: liquid
- Details on test material:
- Batch number: 1HC1502005
Constituent 1
Study design
- Analytical method:
- high-performance liquid chromatography
Results and discussion
Partition coefficient
- Type:
- log Pow
- Partition coefficient:
- 2.59
- Temp.:
- 30 °C
- Remarks on result:
- other: pH not reported
- Details on results:
- y = 1.3594x + 1.7729
R² = 0.9367
log k = 0.599; log Pow = 2.59
confidence interval at 95%
Any other information on results incl. tables
Substance average of retention times tR [min] retention factor k = (tR – t0) / t0 log k Log Pow
thiourea 1.455
2',4',6'-trihydroxyacetophenone 2.664 0.499 -0.080 1.79
acetophenone 3.599 0.674 0.168 1.70
2',6'-dihydroxyacetophenone 3.956 0.899 0.235 2.27
chlorobenzene 11.665 1.177 0.846 2.80
benzophenone 15.305 2.069 0.979 3.20
1,4-dichlorobenzene 23.422 3.606 1.179 3.40
hexachloroacetone 7.231 3.970 0.599 2.59
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
