Registration Dossier
Registration Dossier
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EC number: 208-523-8 | CAS number: 532-02-5
Short-term toxicity to aquatic invertebrates
Administrative data
- Endpoint:
- short-term toxicity to aquatic invertebrates
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- other: Prediction model
- Title:
- Short-term toxicity to aquatic invertebrates by ECOSAR Version 1.10
- Author:
- ECOSAR Version 1.10
- Year:
- 2 016
- Bibliographic source:
- ECOSAR v1.1 Class-specific Estimations, Environmental Protection Agency (EPA) office of Chemical Safety and Pollution Prevention
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Modeling database
- Principles of method if other than guideline:
- ECOSAR v1.1
- GLP compliance:
- no
Test material
- Reference substance name:
- Sodium naphthalene-2-sulphonate
- EC Number:
- 208-523-8
- EC Name:
- Sodium naphthalene-2-sulphonate
- Cas Number:
- 532-02-5
- Molecular formula:
- C10H8O3S.Na
- IUPAC Name:
- sodium naphthalene-2-sulphonate
- Details on test material:
- - Name of test material (as cited in study report): Sodium naphthalene-2-sulphonate
- Substance type: Organic
Constituent 1
Sampling and analysis
- Analytical monitoring:
- no
Test solutions
- Vehicle:
- no
Test organisms
- Test organisms (species):
- Daphnia magna
Study design
- Test type:
- static
- Water media type:
- freshwater
- Total exposure duration:
- 48 h
Results and discussion
Effect concentrations
- Duration:
- 48 h
- Dose descriptor:
- EC50
- Effect conc.:
- 49 421.05 mg/L
- Nominal / measured:
- estimated
- Conc. based on:
- test mat.
- Basis for effect:
- mobility
Applicant's summary and conclusion
- Conclusions:
- Based on the QSAR prediction done using the EPI Suite ECOSAR version 1.10, the 48 hours EC50 was estimated to be 49421.05 mg/L on Daphnia Magna for substance Sodium naphthalene-2-sulphonate with immobilization effects. Thus based on this value it can be concluded that the substance can be classified as non hazardous as per the criteria of CLP regulation.
- Executive summary:
Based on the QSAR prediction done using the EPI Suite ECOSAR version 1.10, the 48 hours EC50 was estimated to be 49421.05 mg/L on Daphnia Magna for substance Sodium naphthalene-2-sulphonate with immobilization effects. Thus based on this value it can be concluded that the substance can be classified as non hazardous as per the criteria of CLP regulation.
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