Registration Dossier
Registration Dossier
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EC number: 204-120-6 | CAS number: 115-99-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: One page summary of results only with very little detail.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 962
- Report date:
- 1962
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Miller and Tainter (Proc. Soc. Exptl. Biol. Hed. 57:261, 1944)
- GLP compliance:
- no
- Remarks:
- study pre-dates introduction of GLP
Test material
- Reference substance name:
- Linalyl formate
- EC Number:
- 204-120-6
- EC Name:
- Linalyl formate
- Cas Number:
- 115-99-1
- Molecular formula:
- C11H18O2
- IUPAC Name:
- linalyl formate
- Reference substance name:
- Linalyl acetate
- EC Number:
- 204-116-4
- EC Name:
- Linalyl acetate
- Cas Number:
- 115-95-7
- Molecular formula:
- C12H20O2
- IUPAC Name:
- 1,5-dimethyl-1-vinylhex-4-en-1-yl acetate
- Reference substance name:
- Linalool
- EC Number:
- 201-134-4
- EC Name:
- Linalool
- Cas Number:
- 78-70-6
- Molecular formula:
- C10H18O
- IUPAC Name:
- 3,7-dimethylocta-1,6-dien-3-ol
- Test material form:
- liquid
Constituent 1
impurity 1
impurity 2
- Specific details on test material used for the study:
- Compound: Linalyl Formate
Test animals
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
- Vehicle:
- not specified
- Details on study design:
- The compounds were administered orally to groups of 5 mice at three or more dose levels. The animals were observed for hypnosis and mortality.
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 5.9 mL/kg bw
- Based on:
- test mat.
Applicant's summary and conclusion
- Interpretation of results:
- GHS criteria not met
- Conclusions:
- Linalyl Formate was found to have an LD50 of 5.9 mL/kg.
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