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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Administrative data

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
experimental study
Adequacy of study:
key study
Study period:
from 1 to 3 September 2004
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004
Report date:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl 1-[(2’-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate
EC Number:
604-137-2
Cas Number:
139481-44-0
Molecular formula:
C25H21N3O3
IUPAC Name:
Methyl 1-[(2’-cyanobiphenyl-4-yl)methyl]-2-ethoxy-1H-benzimidazole-7-carboxylate

Test solutions

Vehicle:
yes

Test organisms

Test organisms (species):
Daphnia magna
Details on test organisms:
Sex: female

Study design

Test type:
static
Water media type:
other: reconstituted water
Limit test:
yes
Total exposure duration:
48 h

Test conditions

Hardness:
2.5 mmol/L (=250.0 mg/L) as CaCO3
Test temperature:
21 °C
pH:
7.8 - 8.1
Dissolved oxygen:
8.7 - 7.4
Conductivity:
< 5 μScm-1
Nominal and measured concentrations:
CaCl2 x 2H2O: 2.0 mmol/L (= 294.0 mg/L)MgSO4 x 7H2O: 0.5 mmol/L (= 123.0 mg/L)NaHCO3: 0.75 mmol/L (= 65.0 mg/L)KCl: 0.075 mmol/L (= 5.8 mg/L)

Results and discussion

Effect concentrationsopen allclose all
Key result
Duration:
48 h
Dose descriptor:
NOEC
Effect conc.:
>= 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility
Key result
Duration:
48 h
Dose descriptor:
LOEC
Effect conc.:
> 100 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mobility

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
After 24 hours in the control and in the test concentration no mortality or immobilization of the test animals was observed.After 48 hours in the control and in the test concentration no mortality or immobilization of the test animals was observed.