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The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Long-term toxicity to fish

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Administrative data

Endpoint:
long-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Comparable to guideline study with acceptable restrictions

Data source

Referenceopen allclose all

Reference Type:
publication
Title:
Toxicity of Chlorinated Benzenes to Fathead Minnows (Pimephales promelas)
Author:
Carlson AR & Kosian PA (1987): Arch. Environ. Contam. Toxicol. 16, 129-135
Year:
1987
Bibliographic source:
Arch. Environ. Contam. Toxicol. 16, 129-135
Reference Type:
grey literature
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: APHA (1971): Standard Methods for the examination of water and wastewater
Deviations:
not specified
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
5431-73-1
IUPAC Name:
5431-73-1
Constituent 2
Chemical structure
Reference substance name:
1,3-dichlorobenzene
EC Number:
208-792-1
EC Name:
1,3-dichlorobenzene
Cas Number:
541-73-1
Molecular formula:
C6H4Cl2
IUPAC Name:
1,3-dichlorobenzene
Test material form:
other: liquid
Details on test material:
- Purity: 98 % (Aldrich Chemical Company, Milwaukee,USA)
- Emipical formula: C5H4Cl2
- Molecular mass: 147 g/mole

Sampling and analysis

Analytical monitoring:
yes
Details on sampling:
not reported

Test solutions

Vehicle:
not specified
Details on test solutions:
Lake Superior water was sand filtered, heated.

Test organisms

Test organisms (species):
Pimephales promelas
Details on test organisms:
- Age: 4 - 12 hours
- Life stage: embryo(s)

Study design

Test type:
not specified
Water media type:
freshwater
Remarks on exposure duration:
until hatch

Test conditions

Hardness:
44-46 mg CaCO3/L = 2.5 - 2.6 °dH
Test temperature:
25 +/- 2°C
pH:
7.3 - 7.6
Dissolved oxygen:
6.9 +/- 0.6 (5.6-8.2) mg/L
Details on test conditions:
- Live brine shrimp nauplii Artemia salina were fed two or three times daily
- The fish were not fed the last 24 hours of the test
- Chambers were cleaned as needed

Results and discussion

Effect concentrationsopen allclose all
Duration:
32 d
Dose descriptor:
NOEC
Effect conc.:
1 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
other: growth
Duration:
32 d
Dose descriptor:
NOEC
Effect conc.:
2.4 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality
Remarks on result:
other: until hatch
Duration:
32 d
Dose descriptor:
LOEC
Effect conc.:
2.3 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

Applicant's summary and conclusion

Validity criteria fulfilled:
not specified
Conclusions:
The toxicity to fish (pimephales promelas) of 1,3-dichlorobenzene was determined at a NOEC (mortality) of 2.4 mg/L until hatch, a NOEC (growth) of 1 mg/L and a LOEC (mortality) of 2.3 mg/L after 32 days.
Executive summary:

The acute toxicity to fish (Pimephales promelas) of 1,3-dichlorobenzene was determined according to a national standard method " APHA (1971): Standard Methods for the examination of water and wastewater" and showed results at a NOEC (mortality) of 2.4 mg/L until hatch, a NOEC (growth) of 1 mg/L and a LOEC (mortality) of 2.3 mg/L after 32 days.