Registration Dossier
Registration Dossier
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EC number: 944-260-1 | CAS number: -
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Acute aquatic toxicity on Daphnia of the target chemical was estimated by using the following predictors: VEGA EPA and DEMETRIA models and ECOSAR.
The predictors were employed in order to apply a weight of evidence approach to enhance the reliability of the predictions. In the weight of evidence assessment only reliable predictions are to be taken into account. 48-h LC50predictions are the following:3.63 mg/L (VEGA/EPA – moderate reliable), 40.24 mg/L (VEGA/DEMETRIA – moderate reliable) and2527.445 mg/L (ECOSAR).
The weight of evidence assessmentled to a48-h LC50prediction for acute aquatic toxicity in Daphnia equal to 3.63 mg/L. The weight of evidence prediction was assessed as moderate reliable.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 3.63 mg/L
Additional information
The prediction was provided on the substance2-Benzyl-4-(dimethylamino)butanoic acid, the acid form of the substance in the object of the registration.
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