Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
surface tension
Data waiving:
study scientifically not necessary / other information available
Justification for data waiving:
the study does not need to be conducted because water solubility is below 1 mg/L at 20°C
Cross-reference
Reason / purpose for cross-reference:
reference to other study
Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
10 May - 29 August 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
GLP compliance:
yes (incl. QA statement)
Type of method:
flask method
Specific details on test material used for the study:
Name (as stated in the report): Velvione
Batch: VE00413992
Expiration date: January 01, 2017
Key result
Water solubility:
0.65 mg/L
Conc. based on:
test mat.
Temp.:
20 °C
pH:
>= 6.3 - <= 6.4
Details on results:
At test end the pH values of the solutions in ultrapure water were pH 6.3, pH 6.4 on two independent flasks.
Conclusions:
The test shows that there is no significant change of the measured concentrations after 288 h, 312 h and 336 h. Thus it can be concluded that equilibrium is reached. Thus the results obtained after 288 h, 312 h and 336 h were averaged, to give the water solubility of Velvione. After rounding off: Solubility of Velvione in water at 20°C: 0.65 mg/l
Executive summary:

The solubility of Velvione in ultrapure water was determined according to the OECD Guideline No. 105 (flask method).

The result is: Solubility in water: 0.65 mg/l at 20°C

 This result corresponds to the saturation mass concentrations of Velvione in ultrapure water at 20°C.

 

Data source

Materials and methods

Results and discussion

Applicant's summary and conclusion