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Diss Factsheets

Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2016-11-21
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
study well documented, meets generally accepted scientific principles, acceptable for assessment
Qualifier:
no guideline followed
Principles of method if other than guideline:
The particle size distribution was determined using Malvern Mastersizer 2000.
GLP compliance:
yes
Type of method:
other: Mastersizer
Type of particle tested:
primary particle
Specific details on test material used for the study:
Batch No.: 2000820462
Key result
Percentile:
D50
Mean:
< 214.367 µm
Remarks on result:
other: Tested as received
Percentile:
D10
Mean:
< 17.987 µm
Remarks on result:
other: Tested as received
Percentile:
D90
Mean:
< 606.991 µm
Remarks on result:
other: Tested as received
Percentile:
D10
Mean:
< 3.621 µm
Remarks on result:
other: Tested hand milled
Percentile:
D50
Mean:
< 18.313 µm
Remarks on result:
other: Tested hand milled
Percentile:
D90
Mean:
< 119.218 µm
Remarks on result:
other: Tested hand milled
Conclusions:
The particle size distribution was determined using Malvern Mastersizer 2000. 50% test substance is less than 214.367 μm when tested as received.
Executive summary:

The particle size distribution was determined using Malvern Mastersizer 2000. 50% test substance is less than 214.367 μm when tested as received and 18.313μm when tested hand milled.

Description of key information

The particle size distribution was determined using Malvern Mastersizer 2000. 50% test substance is less than 214.367 μm when tested as received.

Additional information