Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Administrative data

Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according to OECD / EU guidelines

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2006

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 201 (Alga, Growth Inhibition Test)
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
1-chloro-3-(4-chlorophenoxy) benzene
EC Number:
614-477-3
Cas Number:
6842-62-2
Molecular formula:
C12 H8 Cl2 O
IUPAC Name:
1-chloro-3-(4-chlorophenoxy) benzene

Sampling and analysis

Analytical monitoring:
yes

Test organisms

Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
72 h

Results and discussion

Effect concentrationsopen allclose all
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.024 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
LOEC
Effect conc.:
0.024 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.017 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
0.028 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
LOEC
Effect conc.:
0.047 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
NOEC
Effect conc.:
0.024 mg/L
Nominal / measured:
meas. (arithm. mean)
Conc. based on:
test mat.
Basis for effect:
growth rate

Any other information on results incl. tables

After 72 h algae were transferred from concentrations 0.0243 - 0.0970 mg/L and control to fresh untreated medium and allowed to grow for further 2 - 4 d under test conditions. The test item effect was observed to be reversible at these concentrations. Therefore, there is potential for recovery following exposure up to 0.0970 mg/L (highest test concentration).

Applicant's summary and conclusion

Conclusions:
In the study according to OECD Guideline 201 3,4’-Dichlordiphenylether was found to inhibit the growth of the freshwater green
alga Desmodesmus subspicatus at mean measured test item concentrations = 0.0243 mg/L
(biomass growth) and = 0.0473 mg/L (growth rate). The EC50-values with 95 % confidence intervals
for inhibition of biomass growth (EbC50) and specific growth rate (ErC50) after 72 h were 0.0237
(0.0229 - 0.0245) and 0.0284 (0.0276 - 0.0291) mg/L, respectively.
Inhibition effects were found to be reversible up to 0.0970 mg/L, the highest tested concentration.
All effect levels are given based on mean measured concentrations of the test item 3,4’-
Dichlordiphenylether.