Mecoprop

Density

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

density, other

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

15 April 1999 to 23 June 1999

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Key result

Type:

density

Density:

1.37 g/cm³

Temp.:

23 °C

Results of the Study

Parameter	Determination 1	Determination 2
w1	13.60591	14.88333
w2	23.90942	24.33888
w3	14.59071	15.73862
w4	24.17690	24.57151
W1	10.30351	9.45555
W2	0.98480	0.85529
W3	9.58619	8.83289
W4	0.71732	0.62266
Vs	0.71876	0.62391
D	1.370	1.371
Mean D	1.37

Conclusions:

Under the conditions of this study, the density of the test material was found to be 1.37 g/cm^3 at 23 °C.

Executive summary:

The density of the test material was investigated in accordance with the standardised guideline OECD 109, under GLP conditions.

A clean, dry pycnometer was accurately weighed (w1) then filled to the limits of its capacity with 0.1 % v/v Tween 80. It was then carefully stoppered without trapping air, dried and re-weighed (w2). To the clean, dry and accurately weighed pycnometer, test material (approximately 1 g) was added. The pycnometer was re-weighed (w3) and then the test material covered with displacement liquid. After vigorous shaking of the stoppered pycnometer to suspend the test material, the pycnometer was filled with displacement liquid, stoppered and weighed as before (w4). Two tests were performed concurrently using separate pycnometers.

Under the conditions of this study, the density of the test material was found to be 1.37 g/cm^3 at 23 °C.

Reference 2

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

24 January 1991 to 29 April 1991

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

pycnometer method

Type:

relative density

Density:

1.302 other: dimensionless

Temp.:

20 °C

Results

Parameter	Determination 1	Determination 2
w1	13.84615	15.39910
w2	15.64675	17.88037
w3	24.65433	26.56124
w4	24.23652	25.97717
W1	10.39037	10.57807
W2	1.80060	2.48127
W3	9.00758	8.68087
W4	1.38279	1.89720
Vs	1.38556	1.90100
D(T/4)	1.29955 (1.300)	1.30524 (1.305)
Mean D(T/4)	1.30240 (1.302)

Thus the relative density of the test material was determined to be 1.302 (mean of 1.300 and 1.305) at 20 °C.

Conclusions:

Under the conditions of this study, the relative density of the test material at 20 °C was determined to be 1.302.

Executive summary:

The relative density of the test material was investigated in accordance with the standardised guidelines OECD 109 and EU Method A3, under GLP conditions.

The determination was performed using a pycnometer at 20 °C. Distilled water was used as the displacing liquid. A preliminary determination of the solubility of the test material in distilled water was performed, the solubility of <0.1 % (w/v) was considered to be insignificant with respect to the density determination. The density of the test material was calculated to be relative to the density of water at 4 °C (0.998 g/mL).

Under the conditions of this study, the relative density of the test material at 20 °C was determined to be 1.302.

Description of key information

Key Study: Comb (2000)

Under the conditions of this study, the density of the test material was found to be 1.37 g/cm^3 at 23 °C.

Supporting Study: Colwyn (1993)

Under the conditions of this study, the relative density of the test material at 20 °C was determined to be 1.302.

Key value for chemical safety assessment

Relative density at 20C:

1.37

Additional information

Key Study: Comb (2000)

The density of the test material was investigated in accordance with the standardised guideline OECD 109, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

A clean, dry pycnometer was accurately weighed (w1) then filled to the limits of its capacity with 0.1 % v/v Tween 80. It was then carefully stoppered without trapping air, dried and re-weighed (w2). To the clean, dry and accurately weighed pycnometer, test material (approximately 1 g) was added. The pycnometer was re-weighed (w3) and then the test material covered with displacement liquid. After vigorous shaking of the stoppered pycnometer to suspend the test material, the pycnometer was filled with displacement liquid, stoppered and weighed as before (w4). Two tests were performed concurrently using separate pycnometers.

Under the conditions of this study, the density of the test material was found to be 1.37 g/cm^3 at 23 °C.

 

Supporting Study: Colwyn (1993)

The relative density of the test material was investigated in accordance with the standardised guidelines OECD 109 and EU Method A3, under GLP conditions. The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).

The determination was performed using a pycnometer at 20 °C. Distilled water was used as the displacing liquid. A preliminary determination of the solubility of the test material in distilled water was performed, the solubility of <0.1 % (w/v) was considered to be insignificant with respect to the density determination. The density of the test material was calculated to be relative to the density of water at 4 °C (0.998 g/mL).

Under the conditions of this study, the relative density of the test material at 20 °C was determined to be 1.302.