Registration Dossier
Registration Dossier
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EC number: 228-589-1 | CAS number: 6300-50-1
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2017
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- comparable to guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: Laboratory-SOP A-AF010
- Principles of method if other than guideline:
- - Principle of test: The method is a based on the sieving of the powder using a set of sieves of different mesh
- Apparatus: Set of 3 sieves with a diameter of 200 mm. The mesh size is 450, 150 and 75 μm. Vibrator sieves device. Analytical balance with 0.01 g of precision
- Short description of test conditions: Weigh 20 ± 0.02 grams of sample. Mount sieve set from high (upper) to low mesh size on the vibrator device.
Switch on the vibrator device for 10 minutes.
- Parameters analysed / observed: Weigh the amount of powder retained in each sieve. - GLP compliance:
- no
- Type of method:
- sieving
- Type of particle tested:
- agglomerate
- Type of distribution:
- mass based distribution
- Mass median aerodynamic diameter:
- 450 µm
- No.:
- #1
- Size:
- 75 µm
- Distribution:
- 93.8 %
- No.:
- #2
- Size:
- 150 µm
- Distribution:
- 76.5 %
- No.:
- #3
- Size:
- 450 µm
- Distribution:
- 50.8 %
- Conclusions:
- The mass median diameter of the particles is 450 μm
Reference
The percent mass below 75 micrometer is 6.2%
Description of key information
The particles size determination is a based on the sieving of the powder using a set of sieves of different mesh.
The mass median diameter of the particles determined by sieving is 450 μm: the powder is considered to be of medium volatility.
Additional information
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