Registration Dossier
Registration Dossier
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EC number: 211-112-6 | CAS number: 629-82-3
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
In the only available (and reliable) study according to OECD test guideline 211, the long-term toxicity of the test substance to Daphnia was determined to be NOEC 12.5 mg/l.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 12.5 mg/L
Additional information
The long-term toxicity of the test substance to Daphnia magna was investigated in a study according to OECD test guideline 211 under GLP. Daphnia were exposed to the test substance, prepared by 24h stirring and subsequent filtering, for 21 days in a semi-static test.
As the analytical measurements were not reproducible (probably due to low solubility and hogh lipophilicity),
nominal concentrations were reported. All validity criteria (no immobilised Daphnia in control group with a mean offspring of 120 (> 60) and a variation of CV=16.1%) were met.Nomortality/immobility was observed, while effects on reproduction rate of Daphnia magna were observed at 25.0 mg/L and higher.The NOEC was determined to be 12.5 mg/l (nominal).
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