Registration Dossier
Registration Dossier
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EC number: 701-388-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Two reliable repeated dose toxicity studies were conducted in rats in which the substance was administered for 28 and 90 days respectively both via oral gavage. Minimal effects were observed in those studies, however these effects were not considered to be adverse and the NOAEL for both studies is 1000 mg/kg bw/day.
Key value for chemical safety assessment
Repeated dose toxicity: via oral route - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- NOAEL
- 1 000 mg/kg bw/day
- Study duration:
- subchronic
- Species:
- rat
- Quality of whole database:
- Sufficient to address requirements.
Repeated dose toxicity: inhalation - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: inhalation - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - systemic effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Repeated dose toxicity: dermal - local effects
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Based on the findings of reliable sub-acute and sub-chronic toxicity studies conducted on the substance, classification is not justified.
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