Registration Dossier
Registration Dossier
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EC number: 675-664-3 | CAS number: 39149-80-9
Endpoint summary
Administrative data
Description of key information
Experimental data on the potential of skin corrosion or irritation of TBBP are not available.
QSAR Toolbox has identified one structural alert for skin irritation. Substances with "Aliphatic alpha-halogen-esters" structural alert can cause irritation of the skin as proposed by Hulzebos et al.
In order to estimates skin irritatiion potential from physicochemical property ranges and structural rules, the software Toxtree (v.2.6.13) has been used and the substance has been predicted as a skin irritant.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no study available
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Respiratory irritation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
Available data (i) mechanistic profile (QSAR Toolbox) and (ii) Toxtree prediction are deemed sufficient for classify the substance as Skin Irrit. 2; H315.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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