Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 940-441-4 | CAS number: -
Direct observations: clinical cases, poisoning incidents and other
Administrative data
- Endpoint:
- direct observations: clinical cases, poisoning incidents and other
- Type of information:
- migrated information: read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Publication, reasonably documented, acceptable for assessment
- Justification for type of information:
- The Reporting Format for the Chemical Category According to ECHA (2008) Guidance R.6.2.6.2 can be found in the Endpoint Summary of Toxicokinetics, metabolism and distribution.
Data source
Reference
- Reference Type:
- publication
- Title:
- Potential of the rat as a model for predicting iron bioavailability for humans.
- Author:
- Mahoney AW, Hendricks DG
- Year:
- 1 984
- Bibliographic source:
- DOI 10.1016/S0271-5317(84)80067-6 ISSN 0271-5317 Nutrition Res 4(5):913-22.
Materials and methods
- Endpoint addressed:
- basic toxicokinetics
Test material
- Reference substance name:
- Iron sulphate
- EC Number:
- 231-753-5
- EC Name:
- Iron sulphate
- Cas Number:
- 7720-78-7
- Molecular formula:
- FeSO4
- IUPAC Name:
- iron(2+) sulfate
Constituent 1
Results and discussion
- Results of examinations:
- Iron absorption in the rat is higher than in humans; consequently, rat studies are considered unreliable models for iron toxicology in humans.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
