Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2007
Report date:
2007

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7200 (Melting Point / Melting Range)
Deviations:
no
GLP compliance:
yes
Type of method:
method to determine freezing temperature

Test material

Constituent 1
Reference substance name:
Melaleuca alternifolia, ext.
EC Number:
285-377-1
EC Name:
Melaleuca alternifolia, ext.
Cas Number:
85085-48-9
Molecular formula:
Not applicable (a generic molecular formula cannot be provided for this specific UVCB substance).
IUPAC Name:
Essential oil of melaleuca alternifolia
Test material form:
liquid
Specific details on test material used for the study:
- Purity: 100%
- Lot (batch) No.: 1215
- Expiration date of the lot: 30 March 2009
- Storage condition of test material: Room temperature, protected from light.

Results and discussion

Melting / freezing point
Melting / freezing pt.:
-22 °C

Any other information on results incl. tables

A freezing point for Tea Tree Oil of -22°C was determined (mean of -22°C and -22°C) as indicated by a plateau region in the cooling curve at this temperature (see attached Fig. 1 for a typical cooling curve).

Applicant's summary and conclusion

Conclusions:
The freezing point of Tea Tree Oil was found to be -22°C.
Executive summary:

A GLP-compliant study was carried out to determine the freezing temperature of Tea Tree Oil. The study followed the requirements of EEC method A1, OECD method 102 and OPPTS method 830.7200 without significant deviation. The freezing point of Tea Tree Oil was found to be -22°C.