Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2000
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Remarks:
surrogate substance corn oil, which characterization is similar to corn oil oxidized : identical fatty acids and same content.

Data source

Reference
Reference Type:
other: QSAR model EPI
Title:
EPI suite V4.11
Author:
US EPA
Year:
2000
Bibliographic source:
https://www.epa.gov/tsca-screening-tools/download-epi-suitetm-estimation-program-interface-v411

Materials and methods

Test guideline
Qualifier:
no guideline required
Principles of method if other than guideline:
QSAR : KowWin estimation (EPI)
GLP compliance:
no
Remarks:
not applicable
Type of method:
calculation method (fragments)
Partition coefficient type:
octanol-water

Test material

Constituent 1
Reference substance name:
Reference substance 001
Cas Number:
8001-30-7

Results and discussion

Partition coefficient
Key result
Type:
log Pow
Partition coefficient:
23.08
Remarks on result:
other: temp. and pH are not mentionned on corn oil EPI suite monography.

Applicant's summary and conclusion

Conclusions:
Corn oil characterization is identical to corn oil peroxidized : identical fatty acids and same content.
According to EPISuite, corn oil Log Pow is equal to 23.08.
Hence, peroxidized corn oil Log pow is suggested to be similar to corn oil, which means near to 23.

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