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Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, C.7
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate
EC Number:
419-040-9
EC Name:
2-mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate
Cas Number:
89604-92-2
Molecular formula:
C20H22N4O4S3
IUPAC Name:
tert-butyl 2-{[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-(1,3-benzothiazol-2-ylsulfanyl)-2-oxoethylidene]amino]oxy}-2-methylpropanoate

Results and discussion

Transformation products:
not specified
Remarks:
n.a.
Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
1.8 h
pH:
7
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
3.8 h
pH:
9
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
0.1 h
Other kinetic parameters:
The rate constant of the hydrolysis at pH 9 was calculated
according to a reaction of 2. range.

Applicant's summary and conclusion