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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
hydrolysis
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed
Year:
1996

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, C.7
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate
EC Number:
419-040-9
EC Name:
2-mercaptobenzothiazolyl-(Z)-(2-aminothiazol-4-yl)-2-(tert-butoxycarbonyl) isopropoxyiminoacetate
Cas Number:
89604-92-2
Molecular formula:
C20H22N4O4S3
IUPAC Name:
tert-butyl 2-{[(Z)-[1-(2-amino-1,3-thiazol-4-yl)-2-(1,3-benzothiazol-2-ylsulfanyl)-2-oxoethylidene]amino]oxy}-2-methylpropanoate

Results and discussion

Transformation products:
not specified
Remarks:
n.a.
Dissipation DT50 of parent compoundopen allclose all
pH:
4
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
1.8 h
pH:
7
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
3.8 h
pH:
9
Temp.:
50 °C
Hydrolysis rate constant:
0 s-1
DT50:
0.1 h
Other kinetic parameters:
The rate constant of the hydrolysis at pH 9 was calculated
according to a reaction of 2. range.

Applicant's summary and conclusion