Resinoid of Styrax tonkinensis (Styracaceae) obtained from exudate by ethanol extraction

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From 20 to 27 July 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

2012

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Version / remarks:

2008

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

GLP compliance programme (inspected on 13 and 14 October 2014 / signed on 08 April 2015)

Type of method:

pycnometer method

Key result

Type:

density

Density:

ca. 1.222 g/cm³

Temp.:

20 °C

Remarks on result:

other: the mean of two values

Key result

Type:

relative density

Density:

1.222 other: unitless

Temp.:

20 °C

Presentation of Results

Results of the single determinations with the respective error as well as the mean value and its standard deviation are presented in the following tables:

Table 4.4/1.- Results of Single Determinations

Determination	Density in g/cm^3	Error of Determ. in g/cm^3
1	1.2219	0.0003
2	1.2223	0.0003

Table 4.4/2.-Results – Mean Values

Parameter	Value	Unit	Standard Deviation	Relative Standard Deviation
Volume of Pycnometer	50.47	cm^3	0.0024	0.00%
Density of Test Item	1.2221	g/cm^3	0.0003	0.02%
Density of Test Item	1222.1	kg/m^3	0.3	0.02%
Relative Density of Test Item	1.2221		0.0003	0.02%

 

Discussion:

The density of the test item was calculated as 1.2221 ± 0.0003 g/cm³at 20.0 ± 0.4°C, which is the mean of two values.Precision of the value is given as maximal error of a single determination.

Standard deviation was 0.0003 g/cm³showing very good correlation of the two determinations.

Conclusions:

The test substance is denser than water.
Using the pycnometer method, the density was 1.2221 ± 0.0003 g/cm3 at 20.0 ± 0.4°C

Executive summary:

The density of the test substance was measured according to OECD 109 / EU A3 guideline, using pycnometer method. Two determinations were performed and the mean value was retained.

Description of key information

The test substance is denser than water.

Using the pycnometer method, the density was 1.2221± 0.0003 g/cm at 20.0 ± 0.4°C

Key value for chemical safety assessment

Relative density at 20C:

1.222

Additional information

A fully reliable experimental study, conducted according to OECD 109 /EU A3 guideline, using pycnometer method and under GLP, is available. It is considered as a key study, and the result is retained as key data.