Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 205-502-5 | CAS number: 141-79-7
Dermal absorption
Administrative data
- Endpoint:
- dermal absorption
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- other information
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- publication
- Title:
- Dermal absorption potential of industrial chemicals: criteria for skin notation
- Author:
- Fiserova-Bergerova V, Pierce JT, Droz PO
- Year:
- 1 990
- Bibliographic source:
- Am J Ind Med; 17: 617-36
Materials and methods
Test material
- Reference substance name:
- 4-methylpent-3-en-2-one
- EC Number:
- 205-502-5
- EC Name:
- 4-methylpent-3-en-2-one
- Cas Number:
- 141-79-7
- Molecular formula:
- C6H10O
- IUPAC Name:
- 4-methylpent-3-en-2-one
Constituent 1
Results and discussion
Percutaneous absorption
- Remarks on result:
- other: 1.05 mg/cm2/h
Applicant's summary and conclusion
- Executive summary:
Based on its physical chemical properties, the dermal flux of mesityl oxide through human skin was calculated to be 1.05 mg/cm2/h
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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