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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1979
Report date:
1979

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
3,5-bis(benzyloxy)acetophenone
EC Number:
249-315-7
EC Name:
3,5-bis(benzyloxy)acetophenone
Cas Number:
28924-21-2
Molecular formula:
C22H20O3
IUPAC Name:
1-[3,5-bis(benzyloxy)phenyl]ethan-1-one

Test animals

Species:
rat
Sex:
male

Results and discussion

Effect levels
Sex:
male
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Based on:
not specified
Mortality:
No deaths occured at >5000mg/kg (1-14days)
Clinical signs:
No symptoms of dyfunction where seen at dose level >5000mg/kg (1-14days)

Applicant's summary and conclusion

Interpretation of results:
GHS criteria not met
Conclusions:
The acute oral toxicity of dibensyloxyacetophenone has been estiamted in male rats.
The LD 50 after 1 and 14 days was >5000mg/kg
No symptoms of dysfunction were seen at this dose level, and no deaths occured.