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EC number: 946-615-6
CAS number: -
a preliminary feasibility test, the test item could not be dissolved in
any of the organic solvent-water mixes.
only possibility to solve the test object was the use of pure THF, with
the addition of 25 % water the test object precipitated again.
absorption, higher than the blank, was recorded with UV-detector and
without a column, but with a C18 column, or with a RI detector (without
and with column), no signal could
be assigned to the test item.
In a non-GLP pre-test, designed to determine
suitable HPLC conditions, the test item could NOT be dissolved in any of
solvent (methanol, ethanol,
THF) / water mixtures tested, as recommended by OECD 117/EU A24
The determination of partition coefficient
of the test substance was therefore not possible.
Due to very low water solubility, a high
logPow value is considered, as a worst-case.
Experimental determination not feasible.
High log Kow considered (worst-case for bioaccumulation potential).
A fully reliable preliminary test showed that the determination was not
experimentally feasible, as the test item is not soluble in organic
solvents/water mixes. It is considered as a key study.
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