Registration Dossier

Diss Factsheets

Administrative data

First-aid measures

If inhaled: If breathed in, move person into fresh air. If not breathing give artificial respiration Consult a physician. For advice, contact a Poisons Information Centre or a doctor. If conscious, give water to drink.
In case of skin contact: immediately flush with plenty of soap and water for at least 15 minutes. Remove contaminated clothes and shoes. Seek medical attention in event of irritation.
In case of eye contact: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Ensure complete irrigation of the eye by keeping eyelids apart and away from eye and moving the eyelids by occasionally lifting the upper and lower lids. If pain persists or recurs seek medical attention. Removal of contact lenses after an eye injury should only be undertaken by skilled personnel. Get medical aid immediately.
If swallowed: Rinse mouth with water. Immediately give a glass of water. First aid is not generally required. If in doubt, contact a Poisons Information Center or a doctor.
Most important symptoms and effects, both acute and delayed.
The material may still be damaging to the health of the individual, following ingestion, especially where pre-existing organ (e.g. liver, kidney) damage is evident. Present definitions of harmful or toxic substances are generally based on doses producing mortality (death) rather than those producing morbidity (disease, ill-health). Gastrointestinal tract discomfort may produce nausea and vomiting. In an occupational setting however, unintentional ingestion is not thought to be cause for concern.
Direct contact with the eye may cause transient discomfort characterized by tearing or conjunctival redness (as with windburn). Slight abrasive damage may also result. The material may produce foreign body irritation in certain individuals. Persons with impaired respiratory function, airway diseases and conditions such as emphysema or chronic bronchitis, may incur further disability if excessive concentrations of particulate are inhaled.
CHRONIC HEALTH EFFECTS
Skin contact with the material is more likely to cause a sensitization reaction in some persons. Long term exposure to high dust concentrations may cause changes in lung function i.e. pneumoconiosis; caused by particles less than 0,5 micron penetrating and remaining in the lung. Prime symptom is breathlessness; lung shadows show on X-ray.

Fire-fighting measures

Advice for firefighters: Wear breathing apparatus plus protective gloves. Use water delivered as a fine spray to control fire and cool adjacent area. DO NOT approach containers suspected to be hot. Cool fire exposed containers with water spray from a protected location. If safe to do so, remove containers from path of fire. Equipment should be thoroughly decontaminated after use.

Accidental release measures

Personal precautions, protective equipment and emergency procedures
Use personal protective equipment: wear self - contained breathing apparatus, rubber boots and heavy rubber gloves. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
For non-emergency personnel
Use personal protective equipment. Avoid dust formation. Avoid breathing dust. Ensure adequate ventilation.
For emergency responders
Wear self - contained breathing apparatus and protective clothing to prevent contact with skin and eyes.
Environmental precautions - do not let product enter drains.
Methods and material for containment and cleaning up
MINOR SPILLS: Remove all ignition sources. Clean up all spills immediately. Avoid contact with skin and eyes. Control personal contact by using protective equipment. Use dry clean up procedures and avoid generating dust. Place in a suitable, labelled container for waste disposal.
MAJOR SPILLS: Advise personnel in area. Alert Emergency Responders and tell them location and nature of hazard. Control personal contact by wearing protective clothing. Prevent, by any means available, spillage from entering drains or water courses. Recover product wherever possible.
Use dry clean up procedures and avoid generating dust. Collect residues and place in sealed plastic bags or other containers for disposal. Wash area down with large amounts of water. If contamination of drains or waterways occurs, advise emergency services.

Handling and storage

Precautions for safe handling. Avoid all personal contact, including inhalation. Wear protective clothing when risk of exposure occurs. Use in a well-ventilated area. Prevent concentration in hollows and sumps. DO NOT enter confined spaces until atmosphere has been checked. DO NOT allow material to contact humans, exposed food. Avoid contact with incompatible materials.
Keep containers securely sealed when not in use. Avoid physical damage to containers. Always wash hands with soap and water after handling. Work clothes should be laundered separately. Launder contaminated clothing before re-use. Use good occupational work practice. Observe manufacturer's storing and handling recommendations.
Store in a cool, dry place. Store in well-ventilated area away from incompatible substances. Keep container tightly closed when not in use. Recommended storage: lined metal can, lined metal pail/drum, plastic pail, polyliner drum. Store in original containers. Keep containers securely sealed. Check all containers are clearly labelled. Protect containers against physical damage and check regularly for leaks. Keep away from sources of ignition.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:
not dangerous goods
Shippingopen allclose all
Labels:
not dangerous goods
SpecialProvisionsopen allclose all

Inland waterway transport (UN RTDG/ADN(R))

UN number:
not dangerous goods
Shippingopen allclose all
Labels:
not dangerous goods
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Marine transport (UN RTDG/IMDG)

UN number:
not dangerous goods
Shipping information
Proper shipping name and description:
not dangerous goods
Chemical name:
Quinuclidin-3-one oxime hydrochloride
Labels:
not dangerous goods
Remarksopen allclose all

Air transport (UN RTDG/ICAO/IATA)

UN number:
not dangerous goods
Shipping information
Proper shipping name and description:
not dangerous goods
Chemical name:
Quinuclidin-3-one oxime hydrochloride
Labels:
not dangerous goods
Remarksopen allclose all
SpecialProvisionsopen allclose all

Exposure controls / personal protection

Appropriate engineering controls - Local exhaust ventilation is required where solids are handled as powders or crystals; even when particulates are relatively large, a certain proportion will be powdered by mutual friction. Exhaust ventilation should be designed to prevent accumulation and recirculation of particulates in the workplace.
Individual protection measures, such as personal protective equipment
Eye / face protection - For laboratory, larger scale or bulk handling or where regular exposure in an occupational setting occurs: chemical goggles.
Full face shield may be required for supplementary but never for primary protection of eyes.
Contact lenses may pose a special hazard; soft contact lenses may absorb and concentrate irritants. This should include a review of lens absorption and adsorption for the class of chemicals in use and an account of injury experience. DO NOT wear contact lenses.
Skin and body protection - Choose body protection according to the amount and concentration of the dangerous substance at the work place.
Hand protection - The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 and US F739. Suitability and durability of glove type is dependent on usage. Important factors in the selection of gloves include such as: frequency and duration of contact, chemical resistance of glove material, glove thickness and dexterity.
When prolonged or frequently repeated contact may occur, a glove with a protection class of 5 or higher (breakthrough time greater than 240 minutes according to EN 374) is recommended.
When only brief contact is expected, a glove with a protection class of 3 or higher (breakthrough time greater than 60 minutes according to EN 374) is recommended. Contaminated gloves should be replaced.
Other - barrier cream, skin cleansing cream, eye wash unit.
Respiratory protection - where risk assessment shows air-purifying respirators are appropriate use a dust mask type N95 (US) or type P1 (EN 143) respirator. Use respirators and components tested and approved under appropriate government standards such as NIOSH (US) or CEN (EU). Respirators may be necessary when engineering and administrative controls do not adequately prevent exposures. The decision to use respiratory protection should be based on professional judgment that takes into account toxicity information, exposure measurement data, and frequency and likelihood of the worker's exposure - ensure users are not subject to high thermal loads which may result in heat stress or distress due to personal protective equipment (powered, positive flow, full face apparatus may be an option). Certified respirators will be useful for protecting workers from inhalation of particulates when properly selected and fit tested as part of a complete respiratory protection program. Use approved positive flow mask if significant quantities of dust becomes airborne.
Thermal hazards - none.
Hygiene measures - handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday. Wash contaminated clothing before reuse. Discard contaminated shoes. When handling, DO NOT eats, drink or smoke.
Environmental exposure controls. Contact a licensed professional waste disposal service to dispose of this material. Do not let product enter drains.

Stability and reactivity

Reactivity - No dangerous reactions known.
Chemical stability - Stable under recommended storage conditions.
Possibility of hazardous reactions - Avoid contamination with oxidizing agents i.e. nitrates, oxidizing acids, chlorine bleaches, pool chlorine etc.
Conditions to avoid - sources of ignition, moisture, light.
Incompatible materials - strong oxidizing agents.
Hazardous decomposition products - Hazardous decomposition products formed under fire conditions - carbon monoxide CO, carbon dioxide CO2, nitrogen oxides NOx, chlorine Cl2, hydrogen chloride HCl gas and other pyrolysis products typical of burning organic material.

Disposal considerations

Waste treatment methods - Contact a licensed professional waste disposal service to dispose of this material. All waste must be handled in accordance with local, state and federal regulations. Legislation addressing waste disposal requirements may differ by country, state and/ or territory. Each user must refer to laws operating in their area. Note that properties of a material may change in use, and recycling or reuse may not always be appropriate. Recycle wherever possible.
Consult Waste Management Authority for disposal if no suitable treatment or disposal facility can be identified. Dispose in Incineration in a licensed apparatus (after admixture with suitable combustible material). Decontaminate empty containers. Observe all label safeguards until containers are cleaned and destroyed.

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