Registration Dossier
Registration Dossier
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EC number: 234-186-1 | CAS number: 10584-98-2
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
A key study was available for the assessment of the hydrolytic stability of the test material:
Butler & White (2010) DETERMINATION OF GENERAL PHYSICO-CHEMICAL PROPERTIES. Testing Laboratory: Harlan Laboratories Ltd, Shardlow Business Park, London Road, Shardlow, Derbyshire, DE72 2GD, UK. Owner company: Organo Tin REACH Consortium, c/o ReachCentrum, Avenue E. Van Nieuwenhuyse 6, B-1160, Brussels, BELGIUM. Report No.: 3109/0001.
The study was performed according to the guideline OECD 111, and in accordance with GLP. The study was assigned a reliability score of 1.
Less than 10% hydrolysis was observed after 5 days at 50°C, equivalent to a half-life greater than 1 year at 25°C at pH 4, 7 and 9.
Key value for chemical safety assessment
- Half-life for hydrolysis:
- 1 yr
- at the temperature of:
- 25 °C
Additional information
A reliability rating of 1 was assigned to the key study, Butler & White (2010), as the study was conducted in accordance with recognised guidelines (OECD 111) and in compliance with GLP. During the course of the study, less than 10% hydrolysis was observed after 5 days at 50°C, equivalent to a half-life greater than 1 year at 25°C at pH 4, 7 and 9. As the test item was determined to be hydrolytically stable under acidic conditions (t½ > 1 year at 25°C) no additional testing was performed at pH 1.2, 37.0 ± 0.5°C.
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