Registration Dossier
Registration Dossier
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EC number: 229-213-9 | CAS number: 6429-04-5
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
Data source
Reference
- Reference Type:
- publication
- Title:
- TETRAHYDRO-PAPAVERINE AND HOMODIHYDRO-PAPAVERINE ON BLOOD PRESSURE Effect Of
- Year:
- 1 964
- Bibliographic source:
- Archives Internationales de Pharmacodynamie et de Therapie. Vol. 149, Pg. 200
Materials and methods
- Principles of method if other than guideline:
- method not available
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 1-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinolinium chloride
- EC Number:
- 229-213-9
- EC Name:
- 1-(3,4-dimethoxybenzyl)-1,2,3,4-tetrahydro-6,7-dimethoxyisoquinolinium chloride
- Cas Number:
- 6429-04-5
- Molecular formula:
- C20H25NO4.ClH
- IUPAC Name:
- 1-[(3,4-dimethoxyphenyl)methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-ium chloride
- Test material form:
- solid: particulate/powder
1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- oral: unspecified
Results and discussion
Effect levels
- Dose descriptor:
- LD50
- Effect level:
- 700 mg/kg bw
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
