Registration Dossier

Diss Factsheets

Ecotoxicological information

Short-term toxicity to aquatic invertebrates

Currently viewing:

Administrative data

Link to relevant study record(s)

Referenceopen allclose all

Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
other aquatic crustacea: Daphnid
Test type:
other: (Q)SAR
Water media type:
freshwater
Duration:
48 h
Dose descriptor:
LC50
Effect conc.:
0.261 mg/L
Validity criteria fulfilled:
yes
Remarks:
Aliphatic Amines: Maximum LogKow: 5.0 (Daphnid LC50)
Conclusions:
Estimated LC50 (48 h) : 0.26 mg/L
Intermediate substance is estimated to be very toxic to aquatic invertebrates.
Endpoint:
short-term toxicity to aquatic invertebrates
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
QSAR prediction
Guideline:
other: REACH Guidance on (Q)SAR
Principles of method if other than guideline:
(Q)SAR
Test organisms (species):
other aquatic crustacea: Mysid shrimp
Test type:
other: (Q)SAR
Water media type:
saltwater
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
0.055 mg/L
Validity criteria fulfilled:
yes
Remarks:
Imidazoles: Maximum LogKow: 5.0 (LC50)
Conclusions:
Estimated LC50 (48 h) : 0.05 mg/L
Intermediate substance is estimated to be very toxic to aquatic invertebrates.

Description of key information

ECOSAR 1.11: Daphnid: LC50 (48h): 0.261 mg/L / Mysid (Sea water): LC50 (96h): 0.055 mg/L

Danish (Q)SAR Database: Daphnia magna 48h EC50:

Battery: 0.11 mg/L

Leadscope: 0.19 mg/L

ScSAR: 0.02 mg/L

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
0.26 mg/L

Marine water invertebrates

Marine water invertebrates
Effect concentration:
0.05 mg/L

Additional information

Intermediate substance is estimated to be very toxic to aquatic invertebrates.