Miristalkonium chloride

Surface tension

Link to relevant study record(s)

Reference

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

From May 22, 2007 to July 20, 2007

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Deviations:

not specified

Qualifier:

according to guideline

Guideline:

EU Method A.5 (Surface Tension)

Deviations:

not specified

GLP compliance:

yes (incl. QA statement)

Type of method:

OECD harmonised ring method

Specific details on test material used for the study:

Chemical name: C14 ADBAC
Lot/batch number: 612212
Expiry date: 21 December 2009
Percent active substance: 99.1%
Appearance: White powder
Storage conditions: Room temperature

Key result

Surface tension:

ca. 34.5 mN/m

Temp.:

20 °C

Conc.:

1 g/L

Results

Test temperature: 20°C

Solution concentration: 1 g/L

Solution age: Prepared immediately before measurement

Initial values for the surface tension were obtained as soon as possible after transfer of the aqueous solution to the measurement vessel.

Time (minutes)	Surface tension (mN/m)
	Measured		Calibration corrected
	A	B	A	B
0	37	37	37	37
5	37	36.5	37	36.5
10	37	37	37	37
15	37.5	37.5	37.5	37.5
20	37.5	37	37.5	37
25	37.5	37	37.5	37
30	37.5	37.5	37.5	37

From the results there was no apparent time dependence of surface tension after transfer to the measuring vessel. Overall mean calibration corrected surface tension = 37.5 mN/m (to the nearest 0.5 mN/m)

Harkins-Jordan corrected value = 0.00181x²+ 0.862x - 0.285 = 34.5 mN/m, where x = overall mean calibration corrected surface tension (HARKINS and JORDAN, 1930).

Conclusions:

Under study conditions, the surface tension of a 1 g/L aqueous solution of the test substance was found to be 34.5 mN/m at 20°C. As the result is less than 60 mN/m, test substance is considered to be surface active.

Executive summary:

A study was conducted to determine the surface tension of the test substance, C14 ADBAC, according to the OECD Guideline 115 and EU Method A.5, in compliance with GLP. The surface tension of a 1 g/L aqueous solution was determined at 20°C with a surface tension torsion balance using the OECD harmonised ring method. Measurements were made at 5-minute intervals until a constant value (to within 0.5 mN/m) was recorded. From the results there was no apparent time dependence of surface tension after transfer to the measuring vessel. The overall mean calibration corrected surface tension of a 1 g/L aqueous solution of test substance was found to be 37.5 mN/m. Harkins-Jordan corrected value was calculated as 34.5 mN/m. Under study conditions, the surface tension of a 1 g/L aqueous solution of the test substance was found to be 34.5 mN/m at 20°C. As the result is less than 60 mN/m, test substance is considered to be surface active (Sydney 2007).

Description of key information

Surface tension of the test substance was determined using ring method, according to OECD Guideline 115 and EU Method A.5 (Sydney, 2007).

.

Key value for chemical safety assessment

Surface tension:

34.5

in mN/m at 20°C and concentration in mg/L:

1 000