Registration Dossier

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012
Report date:
2012

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
not specified
Type of method:
flask method

Test material

Constituent 1
Chemical structure
Reference substance name:
5'-chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide
EC Number:
202-182-9
EC Name:
5'-chloro-3-hydroxy-2',4'-dimethoxy-2-naphthanilide
Cas Number:
92-72-8
Molecular formula:
C19H16ClNO4
IUPAC Name:
N-(5-chloro-2,4-dimethoxyphenyl)-3-hydroxynaphthalene-2-carboxamide

Results and discussion

Water solubility
Water solubility:
1.5 mg/L
Temp.:
20 °C
pH:
ca. 7.7

Any other information on results incl. tables

Table 1: Results in detail

  Flask No.    Equilibration time at 20 °C [h]    pH of aqueous solution    Test substance content [mg/l]
   1   24 8.5  2.2 
   2   48 8.5  1.4 
   3   72 7.0  1.5 
   mean   --- 1.5 

Applicant's summary and conclusion

Conclusions:
The water solubility of the test substance was determined as 1.5 mg/L at 20°C.
Executive summary:

The water solubility of the test substance was determined according to OECD 105.

Water solubility (20°C) = 1.5 mg/L (mean).