Registration Dossier
Registration Dossier
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EC number: 240-505-5 | CAS number: 16455-61-1
Endpoint summary
Administrative data
Description of key information
LC50 (96 h): > 120 mg/L [OECD 203; zebrafish (Danio rerio); nominal; read-across substance Fe(Na)EDDHA]
LC50 (96 h): > 100 mg/L [no guideline followed; Rainbow trout, Carp, Catfish and Bluegill; nominal; read-across substance Fe(Na)EDDHA]
EC50(48h): > 120 mg/L (nominal), EC50(48h): > 122 mg/L (measured) [OECD 202; Daphnia magna, read-across substance: Fe(Na)EDDHA]
EC50 (72h) > 294 mg/L (growth rate), NOEC (72h): 8.2 mg/L (growth rate), EC50 (72h): 27.3 mg/L (biomass), NOEC (72h): 2.4 mg/L (biomass) [OECD 201; Desmodesmus subspicatus; read-across substance Fe(Na)EDDHA]
EC10 (3h): 450 mg/L, EC50 (3h) > 1000 mg/L [OECD 209; activated sludge; read-across substance: Fe(Na)EDDHA]
Additional information
General consideration
No experimental investigations of o,o-Fe(Na)EDDHA (CAS16455-61-1) are available for relevant aquatic ecotoxicological endpoints. Read-across from the closely related substance Fe(Na)EDDHA (CAS 84539-55-9) was performed instead and is believed to behave very similar in aqueous solutions. For detailed information, please refer to the separate Read-across Statement.
Fish
The acute toxic effects of Fe(Na)EDDHA to zebrafish were investigated in a study according to the principles of OECD Guideline 203 and EU Method C.1. The LC50 for a 96 hour exposure was greater than 120 mg/L and the NOEC was greater than or equal to 120 mg/L for zebrafish.
Daphnia
The acute toxic effects of Fe(Na)EDDHA to Daphnia magna were investigated according to the principles of OECD-Guideline 202 and EU method C.2. The EC50 for a 48 hour exposure was greater than 120 mg/L based on the nominal concentration of the test substance and greater than 122 mg/L based on the mean measured concentrations.
Algae
The 72 hour EC50 value for Fe(Na)EDDHA with the Desmodesmus subspicatus CHODAT (SAG 86.81) was greater than 294 mg/L and the NOEC was 8.2 mg/L based on mean measured concentrations and growth rate.
Microorganisms
The 3 hours EC10 value for the test substance Fe(Na)EDDHA in the Activated Sludge Respiration Inhibition Test was 450 mg/L. The EC50 was greater than 1000 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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