Resinoid of Myroxylon balsamum var. pereirae (Fabaceae) obtained from the exudate by ethanol extraction

Density

Link to relevant study record(s)

Reference

Endpoint:

relative density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

12 December 2017

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

The study was conducted according to an internationally recognised method, and under GLP. The test substance is adequately characterised. Therefore full validation applies.

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Version / remarks:

2012

Deviations:

no

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Version / remarks:

2008

Deviations:

no

Principles of method if other than guideline:

Not applicable

GLP compliance:

yes (incl. QA statement)

Remarks:

Inspected on 4,5 and 6 July 2016/ Signed on 10 January 2017

Type of method:

pycnometer method

Key result

Type:

relative density

Density:

ca. 1.157 other: no dimension

Temp.:

20 °C

Remarks on result:

other: density= 1156.7 kg/m3

Calculation:

Density at 20°C was calculated using the following formula: Density= (M1 +A)/(M2 +A) x r

With    M1: apparent mass of test item necessary to fill the flask at 20°C

M2: apparent mass of water necessary to fill the flask at 20°C

r: water density at 20°C = 998.2 kg/m³as published by the CRC Handbook of Chemistry and Physics, 90rd Edition 2009

A: correction due to air buoyancy

A =d_ax M2

d_a: air relative density (0.0012), value influenced by atmospheric pressure (but usual variations do not affect results of density)

M1 = m1 – m0

M2 = m2 – m0

m0: measured mass of empty pycnometer

m1: measured mass of pycnometer + test item

m2: measured mass of pycnometer + water

 

The relative density D²⁰₄is the ratio between the density of the test item determined at 20°C, and the density of water at 4°C which is 1000 kg/m³. The relative density has no dimension.

Results:

Results of the two determinations are reported in the following table:

Measurement	Determination
	1	2
Temperature (°C)	20.0	20.0
Mass of the empty pycnometer (g)(m0)	35.22167	35.22167
Mass of the pycnometer filled with ultrapure water (g)(m2)	60.15084	60.15084
Mass of the pycnometer filled with the test item (g)(m1)	64.10979	64.11858
Density of the test item (kg/m^3)	1156.5	1156.9
Mean Density (kg/m^3)	1156.7 +/-0.3

Conclusions:

The density of the test item was determined to be 1156.7 kg/m3 at 20.0 +/- 0.1°C (mean of two determinations).
The relative density of the test item was determined to be D204 = 1.157.

Executive summary:

The study was performed in order to determine the density of test item according OECD 109, resp. EU A.3 guideline, using a pycnometer.

The density of the test item was determined to be 1156.7 kg/m3 at 20.0 +/- 0.1°C (mean of two determinations).

The relative density of the test item was determined to be D204 = 1.157.

Description of key information

The density of test item was determined to be 1156.7 kg/m3 (relative density D=1.157) at 20°C.

(mean value of two independent determinations)

Key value for chemical safety assessment

Relative density at 20C:

1.157

Additional information

A fully reliable experimental study, conducted according to OECD 109/ EU A3 guideline is available.

It is considered as a key study, and the result is retained as key data.