Registration Dossier
Registration Dossier
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EC number: 232-009-2 | CAS number: 7783-56-4
Endpoint summary
Administrative data
Description of key information
There are five study records for acute toxicity, which are reliable with restrictions: one with oral administration and four with subcutaneous
administration. Further one study record with unclear administration of antimontrifluoride has no sufficient reliability and is therefore not used for assessment.
A mouse LD50 oral 804 mg/kg bw was reported. According to this result a classification for acute toxicity oral in Category 4 based on GHS criteria is recommended.
Key value for chemical safety assessment
Acute toxicity: via oral route
Link to relevant study records
- Endpoint:
- acute toxicity: oral
- Type of information:
- not specified
- Adequacy of study:
- other information
- Study period:
- 1959
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- data from handbook or collection of data
- Remarks:
- RTECS, ChemIDplus
- GLP compliance:
- not specified
- Test type:
- other: not specified
- Species:
- mouse
- Strain:
- not specified
- Sex:
- not specified
- Route of administration:
- oral: unspecified
- Doses:
- not specified
- No. of animals per sex per dose:
- not specified
- Sex:
- not specified
- Dose descriptor:
- LD50
- Effect level:
- 804 mg/kg bw
- Mortality:
- not specified
- Interpretation of results:
- Category 4 based on GHS criteria
- Executive summary:
RTECS and ChemIDplus database entry: mouse LD50 oral 804 mg/kg
Source: Osaka Shiritsu Daigaku Igaku Zasshi.Journal of the Osaka City Medical Center.Vol. 8, Pg. 817, 1959
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 804 mg/kg bw
- Quality of whole database:
- Dose descriptor from collection of data (RTECS-database). Primary source was not available.
Additional information
According to Regulation (EC) No. 1272/2008 and subsequent regulations, the test item is classified as Acute Tox. 3 H301, H311, H331.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
