Registration Dossier
Registration Dossier
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Reaction mass of Cobaltate(2-), [2-[[[4-hydroxy-3-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]sulfonyl]amino]benzoato(3-)][2-[[2-hydroxy-5-[(phenylamino)sulfonyl]phenyl]azo]-3-oxo-N-phenylbutanamidato(2-)]-, disodium and Cobaltate(3-), bis[2-[[[4-hydroxy-3-[[2-oxo-1-[(phenylamino)carbonyl]propyl]azo]phenyl]sulfonyl]amino]benzoato(3-)]-, trisodium and sodium bis[2-[[2-hydroxy-5-[(phenylamino)sulphonyl]phenyl]azo]-3-oxo-N-phenylbutyramidato(2-)]cobaltate(1-)
EC number: 947-257-3 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Aquatic Chronic 2 (H411), according to the CLP Regulation (EC) No 1272/2008
Additional information
Adequate chronic toxicity data is not available for Acid Yellow 235, therefore the aquatic toxicity assessment and classification are based mainly on the short-term toxicity data available on the substance and Similar Substance 01. The usage of information on a structural analogous can be considered as suitable and appropriated; details on the approach followed are included in the document attached to the IUCLID section 13.2.
Acid Yellow 235 is a very water soluble substance, not rapidly degradable. In addition, it is characterized by a negative log Kow, indicating a low potential for bioaccumulation.
According to the CLP Regulation (EC) No 1272/2008, acute aquatic toxicity is normally determined using L(E)C50 data on fish, crustacean and/or an algal species; nevertheless it is also specified in the Regulation that data on other species (e.g. Lemna spp.) shall also be considered if the test methodology is suitable. Data is available for fish Danio rerio, Daphnia magna and Lemna Gibba species; these organisms cover a range of trophic levels and taxa and are considered as surrogate for all aquatic organisms.
No L(E)C50 value was recorded at concentration equal/lower than 1 mg/l, thus the classification criteria for acute (short-term) aquatic hazard (category 1) of the CLP Regulation (EC) No 1272/2008 are not met.
The outcomes of the tests performed on the three trophic levels suggest that fish is the most sensitive species, thus the classification should be based on the short-term toxicity to fish.
According to the CLP Regulation (EC) No 12720/2008 criteria for the identification of the classification categories for hazardous to the aquatic environment, the study about short-term toxicity to fish fixed the short-term effect level on fish between 1 and 10 mg/l.
Therefore, the Acid Yellow 235 is classified as Aquatic Chronic 2 (H411), according to the CLP Regulation (EC) No 1272/2008.
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