Registration Dossier
Registration Dossier
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EC number: 217-576-6 | CAS number: 1892-29-1
Endpoint summary
Administrative data
Description of key information
Experimental data show the test item has a 3 hour NOEC of 3.2 mg/L and EC50 of 612 mg/L for toxicity to aquatic microorganisms, a 72 hour NOEC of 32 mg/L and EC50 of >100 mg/L for algal growth inhibition, a 48 hour EC50 of 4.4 mg/L for toxicity to aquatic invertebrates and a 96-hour LC50 of >100 mg/L for short-term toxicity to fish.
As none of the acute effect concentrations are below 1 mg/L, the substance does not meet the criteria for acute aquatic toxicity category 1 under EU CLP. The NOEC for algal growth inhibition, the only chronic toxicity result, is above the chronic aquatic toxicity criteria for non-rapidly degradable substances of =<1 mg/L for chronic category 2. However, as only limited chronic ecotoxicity data are available, the acute toxicity data have been compared to the chronic classification criteria. As the lowest EC50 is 4.4 mg/L for aquatic invertebrates and the substance is not readily biodegradable, the substance meets the criteria for aquatic chronic category 2 classification. Therefore, the substance is classified for aquatic chronic toxicity category 2.
Additional information
Experimental data are available from three GLP-compliant, guideline studies. The toxicity to aquatic invertebrates was determined in a study following OECD guideline 202 and the short-term toxicity to fish was determined in a study following OECD guideline 203. Algal growth inhibition was determined in a study following OECD 201 and toxicity to aquatic microorganisms was determined in an OECD guideline 209 study on respiration inhibition.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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