Registration Dossier
Registration Dossier
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EC number: 296-117-1 | CAS number: 92257-28-8
Endpoint summary
Administrative data
Description of key information
Biodegradation in water: Biodegradation study was performed of the structurally and functionally similar read across chemicals. The studies are as mentioned below:
Study 1.
Biodegradation study was conducted for evaluating the percentage biodegradability of read across test substance. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to 0.2% by BOD and 0.3 % by GC parameter in 14 days. Thus, based on percentage degradation test chemical is considered to be not readily biodegradable in water.
Study 2.
Similar study was conducted on structurally and functionally similar read across chemical. Biodegradation study was conducted for evaluating the percentage biodegradability of test substance. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to 0 % by BOD and 0 % by HPLC parameter in 28 days. Thus, based on percentage degradation of test chemical is considered to be not readily biodegradable in water.
Thus based on both studies for structurally and functionally similar read across chemicals it can be concluded that the test chemical N-(2-ethylhexyl)-1-[4-(2-phenyldiazen-1-yl)phenyl]naphthalen -2-amine (92257-28 -8) was not readily biodegradable in water.
Additional information
Biodegradation in water:
Various experimental data for the target compound N-(2-ethylhexyl)-1-[4-(2-phenyldiazen-1-yl)phenyl]naphthalen-2-amine (CAS No. 92257-28-8) and supporting weight of evidence studies for its
structurally and functionally similar closest read across substance were reviewed for the biodegradation end point which are summarized as below:
Study 1.
Biodegradation study was conducted for evaluating the percentage biodegradability of read across test substance. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to 0.2% by BOD and 0.3 % by GC parameter in 14 days. Thus, based on percentage degradation test chemical is considered to be not readily biodegradable in water.
Study 2.
Similarly study was conducted on structurally and functionally similar read across chemical. Biodegradation study was conducted for evaluating the percentage biodegradability of test substance. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to 0 % by BOD and 0 % by HPLC parameter in 28 days. Thus, based on percentage degradation of test chemical is considered to be not readily biodegradable in water.
On the basis of above results for target chemical N-(2-ethylhexyl)-1-[4-(2-phenyldiazen-1-yl)phenyl]naphthalen-2-amine (CAS No. 92257-28-8) and for its read across substance from authoritative database, it can be concluded that the test substance N-(2-ethylhexyl)-1-[4-(2-phenyldiazen-1-yl)phenyl] naphthalen-2-amine (CAS No. 92257-28-8) can be expected to be not readily biodegradable in nature.
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