Registration Dossier
Registration Dossier
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EC number: 233-117-2 | CAS number: 10039-33-5
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 (72 hrs) > 0.0018 mg/l (measured, initial) corresponding to 100 % saturated solution; greater than the water solubility of the test material.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 100 mg/L
- EC10 or NOEC for freshwater algae:
- 0.001 mg/L
Additional information
No experimental data is available for the assessment of the toxicity of the substance to aquatic algae and cyanobacteria, therefore data on Similar Substance 01 is used. Justification for Read Across is given in Section 13 of IUCLID.
The toxicity of the test material to aquatic plants was determined in a study conducted in accordance with the standardised guideline OECD 201, using the algal species Desmodesmus subspicatus (reported as Scenedesmus subspicatus). The study was conducted using a range of concentrations of the analogue substance, tested up to the water solubility of the test material. The concentrations of the test material were not maintained in the solutions throughout the entire 72 hour test period, results were therefore expressed as the initial concentration. Under the conditions of the study, the test material exhibited little or no difference on the growth rate of the algae, the ErC50 of the test material is considered to be greater than the water solubility of the test material, >0.0018 mg/l.
The substance is expected to not have any toxic effects on algae in concentrations up to the water solubility.
The substance is considered as highly insoluble in water. No toxic effects were observed up to the limit of water solubility and thus the EC50 is higher than the highest (measured, geom.mean) concentration. The key value used for chemical safety assessment is the highest value considered to be safe for aquatic toxicity according to the CLP Regulation (EC) No.1272/2008, i.e. 100 mg/l.
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