Registration Dossier
Registration Dossier
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EC number: 204-807-0 | CAS number: 126-83-0
Endpoint summary
Administrative data
Description of key information
Additional information
An OECD Guideline for Testing of Chemicals No. 111: "Hydrolysis as a function of pH" was conducted to determine the rate of hydrolysis of Sodium 3-Chloro-2-hydroxy-propanesulfonate (CHPS-NA) at different environmentally relevant pH-values and at different temperatures. The study investigated the hydrolytic behaviour in aqueous solutions buffered at pH 4, 7 and 9. Samples were incubated in the dark. The test substance was found to be hydrolytically stable at pH 4 (DT50 > 1 year at 25°C) and hydrolytically unstable at pH 7 and 9.
It could be concluded that the formation of 2-oxiranemethanesulfonicacid, sodium salt and sodium 2,3-dihydroxypropane-1-sulfonate is highly likely. Furthermore, sodium 2,3-dihydroxypropane-1-sulfonate seems to be the most stable transformation product and thus might be the endpoint of the degradation pathway.
Other abiotic degradation studies, such as phototransformation studies in air, water, and soils, are not required.
Based on biodegradation study conducted in accordance with OECD Guideline 301D, Sodium 3-Chloro-2-hydroxy-propanesulfonate (CHPS-NA) is not readily biodegradable.
Sodium 3-Chloro-2-hydroxy-propanesulfonate (CHPS-NA) attained 2% biodegradation after 28 days and therefore cannot be considered to be readily biodegradable when tested in a closed bottle test according to OECD Guideline No 301D.
The partition coefficient of Sodium 3-Chloro-2-hydroxy-propanesulfonate (CHPS-NA) was determined based on OECD Guideline No 107 and was calculated based on the results of the analytical determination. According to this study, the logarithmic partition coefficient (n octanol/water) of the substance was determined to be -3.81 using the shake flask method at 20 °C.
In accordance with Column 2 adaptation statement of REACH Annex VIII and IX, adsorption/desorption screening and further studies on adsorption/desorption, information requirements 9.3.1 and 9.3.3, may be omitted since the log Kow value for the substance is < 3.0 and has low potential for adsorption (CSR sections 1.3 and 4.2.1).
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