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Physical & Chemical properties

Water solubility

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Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
August 11-13, 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well described GLP compliant study conducted to recognized international test guidelines
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Principles of method if other than guideline:
TOC using persulphate digestion to yield CO2 followed by estimation by IR
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
ca. 1 154 g/L
Temp.:
20 °C
pH:
ca. 0
Remarks on result:
other: Solubility is average of three samples for each of three days
Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
Test substance is soluble
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
July 28-30, 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well described GLP compliant study conducted to recognized international test guidelines
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Principles of method if other than guideline:
TOC using persulphate digestion to yield CO2 followed by estimation by IR
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
ca. 1 318 g/L
Temp.:
20 °C
pH:
ca. 0
Remarks on result:
other: dark colour solution; solubility is average of three samples for each of three days
Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
Test substance is soluble
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 19-23, 2010
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Well described GLP compliant study conducted to recognized international test guidelines
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Principles of method if other than guideline:
TOC using persulphate digestion to yield CO2 followed by estimation by IR
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
ca. 1 156 g/L
Temp.:
20 °C
pH:
ca. 0
Remarks on result:
other: dark colour solution; solubility is average of three samples for each of three days
Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
Test substance is soluble
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
July 21-30, 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well described GLP compliant study conducted to recognized international test guidelines
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Principles of method if other than guideline:
TOC using persulphate digestion to yield CO2 followed by estimation by IR
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
ca. 821 g/L
Temp.:
20 °C
pH:
ca. 0
Remarks on result:
other: silky colour solution; solubility is average of three samples for each of three days
Conclusions:
Interpretation of results (migrated information): moderately soluble (100-1000 mg/L)
Test substance is soluble
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
supporting study
Study period:
July 14-16, 2010
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Well described GLP compliant study conducted to recognized international test guidelines
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Deviations:
no
Principles of method if other than guideline:
TOC using persulphate digestion to yield CO2 followed by estimation by IR
GLP compliance:
yes
Type of method:
column elution method
Water solubility:
ca. 1 117 g/L
Temp.:
20 °C
pH:
ca. 0
Remarks on result:
other: silky colour solution; solubility is average of three samples for each of three days
Conclusions:
Interpretation of results (migrated information): soluble (1000-10000 mg/L)
Test substance is soluble

Description of key information

The water solubilities of the 5 aromatic sulphonic acids were all relatively high; ranging from 1117 to 1318 g/L for all except cumene sulphonic acid which had a solubility of 821 g/L.

Key value for chemical safety assessment

Water solubility:
50 000 mg/L
at the temperature of:
20 °C

Additional information

A representative value for water solubility of 50000 mg/l has been indicated as key value for chemical safety assessment, because 500 is the maximum acceptable value from EUSES 2.0 model for environmental risk assessment