Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2017
Report date:
2017

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
GLP compliance:
yes (incl. QA statement)
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
Zinc bis[p-toluenesulphinate]
EC Number:
246-181-1
EC Name:
Zinc bis[p-toluenesulphinate]
Cas Number:
24345-02-6
Molecular formula:
C14H14O4S2Zn
IUPAC Name:
zinc bis(4-methylbenzenesulfinate)
Test material form:
solid: particulate/powder

Test animals

Species:
rat
Strain:
Wistar
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
corn oil

Results and discussion

Effect levels
Key result
Sex:
female
Dose descriptor:
LD50
Effect level:
ca. 5 000 mg/kg bw
Mortality:
No mortality was observed in any of the animals treated at 2000 mg/kg body weight for Step I and Step II.
Clinical signs:
other: All the animals appeared normal throughout the acclimatization period.
Gross pathology:
No abnormalities were observed in any of the treated animals at terminal sacrifice.

Applicant's summary and conclusion