Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 226-149-3 | CAS number: 5303-24-2
Endpoint summary
Administrative data
Description of key information
Additional information
The experimental dataset for octyl laurate (CAS 5303-24-2) is not complete. Therefore, QSAR predictions were considered for the estimation of the adsorption potential in order to fulfill the standard information requirements laid down in Annex VIII of Regulation (EC) No 1907/2006.
Octyl laurate is characterized by low water solubility (< 0.467 µg/L at 20 °C), a low estimated vapour pressure (1.15E-4 Pa at 20 °C, SPARC v4.6), a high log Kow (7.95 - 8.72, QSAR, VEGA 1.1.3) and a high log Koc (> 4.9, MCI method, KOCWIN v2.00) indicating a high adsorption potential to soil and sediment particles. Experimental results from a standard biodegradation study showed that octyl laurate is readily biodegradable (87% after 28 d, OECD 301 B). According to the Guidance on information requirements and chemical safety assessment, Chapter R.7b, readily biodegradable substances can be expected to undergo rapid and ultimate degradation in most environments, including biological Sewage Treatment Plants (STPs) (ECHA, 2017). Furthermore, the guidance also states that once insoluble chemicals enter a standard STP, they will be extensively removed in the primary settling tank and fat trap and thus, only limited amounts will come into contact with activated sludge organisms. Nevertheless, once this contact takes place, these substances are expected to be removed from the water column to a significant degree by adsorption to sewage sludge (Guidance on information requirements and chemical safety assessment, Chapter R.7a, (ECHA, 2017) and whatever remains will be extensively biodegraded (due to ready biodegradability).
Therefore, only negligible concentrations of the substance are likely to be released into the environment through conventional STPs, if at all, and whatever fraction is released will preferentially distribute into the sediment compartment. The bioavailability of the substance in the sediment compartment is presumably very low based on the physico-chemical properties of the substance (i.e. strong binding properties). Abiotic degradation via hydrolysis and evaporation into the atmospheric compartment are presumably no relevant removal pathways.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
